Study claims ketogenic diet prevents cognitive decline


A new study found that consuming a ketogenic diet, high levels of fat and low levels of carbohydrate can help prevent cognitive decline. The study has been published in the journal Frontiers in Aging Neuroscience. The findings showed that the stomach and the brain are more closely connected than we once thought, and in fact, the health of one can affect the other.

Ai-Ling Lin from the University of Kentucky in the US reportedly said that recent science has suggested that neurovascular integrity might be regulated by the bacteria in the gut, so they set out to see whether the ketogenic diet enhanced brain vascular function and reduced neurodegeneration risk in young healthy mice.

He also said that neurovascular integrity, including cerebral blood flow and blood-brain barrier function, plays a major role in cognitive ability.

The researchers examined the effect of diet on cognitive health on mice, which followed a ketogenic diet regimen for the study. Two groups of nine mice, aged 12-14 weeks, were given either the ketogenic diet or a regular diet.

The team found that after 16 weeks, mice on ketogenic diet had significant increase in cerebral blood flow, improved balance in the microbiome in the gut, lower blood glucose levels and body weight, and a beneficial increase in the process that clears amyloid-beta from the brain — a hallmark of Alzheimer’s disease.

Lin said that the ketogenic diet, in particular, has demonstrated effectiveness in treating certain diseases, we chose to test healthy young mice using diet as a potential preventative measure. They were delighted to see that we might indeed be able to use diet to mitigate risk for Alzheimer’s disease.